TLR2 Polyclonal Antibody

Target Information

Target Name	TLR2
Uniprot ID	O60603
Cellular Localization	Membrane.
Immunogen	Synthetic peptide within Human TLR2 aa 700 to the C-terminus conjugated to keyhole limpet haemocyanin.
Function	Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Product Details

Description	Rabbit polyclonal antibody to TLR2.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Synthetic peptide within Human TLR2 aa 700 to the C-terminus conjugated to keyhole limpet haemocyanin.
Positive Control	IHC-P: Rat ovary tissue. WB: Rat brain and lung lysate.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.09% Sodium Azide Constituent: 50% Glycerol, 1% BSA
Handling	Avoid freeze-thaw cycles.