TLR3 Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	TLR3
Uniprot ID	O15455
Cellular Localization	Endoplasmic reticulum membrane. Endosome membrane.
Immunogen	Recombinant fragment.
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Product Details

Description	Rabbit monoclonal antibody to TLR3 - BSA and Azide Free.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment.
Positive Control	Flow Cyt-intra: Human PBMC treated with 100ng/ml GM-CSF and 50ng/ml IL-4 for 6 days.
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	Constituent: 100% PBS