Cat. No.: IBDA-435241
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Online InquiryTarget Information
Target Name | TLR3 |
Uniprot ID | O15455 |
Cellular Localization | Endoplasmic reticulum membrane. Endosome membrane. |
Immunogen | Recombinant fragment. |
Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Product Details
Description | Rabbit monoclonal antibody to TLR3 - BSA and Azide Free (Detector). |
Host Species | Rabbit |
Clonality | Monoclonal |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse |
Immunogen | Recombinant fragment. |
Application | sELISA |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.2 Constituent: 100% PBS |