Cat. No.: IBDA-435228
Size:
Online InquiryTarget Information
| Target Name | TLR3 |
| Uniprot ID | O15455 |
| Cellular Localization | Endoplasmic reticulum membrane. Endosome membrane. |
| Immunogen | Human Flag-tagged TLR3 stably expressed by Ba/F3 cells. |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Product Details
| Description | Biotin Mouse monoclonal antibody to TLR3. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG1 |
| Conjugation | Biotin |
| Reactivity | Human |
| Immunogen | Human Flag-tagged TLR3 stably expressed by Ba/F3 cells. |
| Positive Control | Monocytes, granulocytes, lymphocytes, human fibroblast, MRC-5 & FS-4 cells. Flow Cyt (Intra): THP-1 cells. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | Preservative: 0.02% Sodium Azide Constituent: PBS, 0.1% BSA |
| Handling | Avoid freeze-thaw cycles. |