Cat. No.: IBDA-435230
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Online InquiryTarget Information
| Target Name | TLR3 |
| Uniprot ID | O15455 |
| Cellular Localization | Endoplasmic reticulum membrane. Endosome membrane. |
| Immunogen | Synthetic peptide within Human TLR3 aa 780-830 (C terminal). |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Product Details
| Description | Rabbit polyclonal antibody to TLR3. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Synthetic peptide within Human TLR3 aa 780-830 (C terminal). |
| Positive Control | IHC-P: Human and mouse spleen tissue. WB: Daudi cell lysate and mouse speen tissue. ICC: Human spleen tissue. |
| Application | ICC, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.02% Sodium Azide Constituent: PBS |