TLR4 Monoclonal Antibody

Target Information

Target Name	TLR4
Uniprot ID	O00206
Cellular Localization	Membrane.
Immunogen	Tissue, cells or virus corresponding to TLR4.
Function	Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.

Product Details

Description	Biotin Rat monoclonal antibody to TLR4.
Host Species	Rat
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG2a
Conjugation	Biotin
Reactivity	Mouse
Immunogen	Tissue, cells or virus corresponding to TLR4.
Application	Flo, FuncS, IHC-Fr, IP

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.02% Sodium Azide Constituent: PBS, 1% BSA
Handling	Avoid freeze-thaw cycles.