Cat. No.: IBDA-435179
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Online InquiryTarget Information
| Target Name | TLR5 |
| Uniprot ID | O60602 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide: SSKDFTWVQN ALLKHLDTQY SDQNRFNLCF EERDFVPGEN RIANIQDAIW NSRKIVCLVS RHFLRDGWCL EAFSYAQGRC LSDLNSALIM VVVGSLSQY QL conjugated to KLH, corresponding to amino acids 700-800 of Human TLR5. |
| Function | Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Product Details
| Description | Mouse monoclonal antibody to TLR5. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Synthetic peptide: SSKDFTWVQN ALLKHLDTQY SDQNRFNLCF EERDFVPGEN RIANIQDAIW NSRKIVCLVS RHFLRDGWCL EAFSYAQGRC LSDLNSALIM VVVGSLSQY QL conjugated to KLH, corresponding to amino acids 700-800 of Human TLR5. |
| Positive Control | Flow Cyt (Intra): Ramos cells WB: Ramos and Raw cell lysate. |
| Application | Flo, ICC, ICC/IF, IHC-Fr, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.05% Sodium Azide Constituent: PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |