Cat. No.: IBDA-431213
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Online InquiryTarget Information
| Target Name | TLR6 |
| Uniprot ID | Q9Y2C9 |
| Cellular Localization | Cell membrane. Cytoplasmic vesicle > phagosome membrane. |
| Immunogen | Synthetic peptide corresponding to 15 amino acids near the amino terminus of the human TLR6 protein. |
| Function | Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. |
Product Details
| Description | Rabbit polyclonal antibody to TLR6. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to 15 amino acids near the amino terminus of the human TLR6 protein. |
| Positive Control | Jurkat whole cell lysate. |
| Application | ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.02% Sodium Azide Constituent: PBS |