Cat. No.: IBDA-431214
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Online InquiryTarget Information
| Target Name | TLR6 |
| Uniprot ID | Q9Y2C9 |
| Cellular Localization | Cell membrane. Cytoplasmic vesicle > phagosome membrane. |
| Immunogen | Fusion protein within Human TLR6 (internal sequence). |
| Function | Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. |
Product Details
| Description | Rabbit polyclonal antibody to TLR6. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Fusion protein within Human TLR6 (internal sequence). |
| Positive Control | Human thyroid cancer and breast cancer tissue |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.4 Preservative: 0.05% Sodium Azide Constituent: 50% Glycerol, 49% PBS |
| Handling | Avoid freeze-thaw cycles. |