Cat. No.: IBDA-431344
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Online InquiryTarget Information
| Target Name | TLR7 |
| Uniprot ID | Q9NYK1 |
| Cellular Localization | Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. |
| Immunogen | Synthetic peptide (Mouse) corresponding to 14 amino acids near the middle of mouse TLR7. |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Product Details
| Description | Rabbit polyclonal antibody to TLR7. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide (Mouse) corresponding to 14 amino acids near the middle of mouse TLR7. |
| Positive Control | Daudi cell lysates |
| Application | ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.02% Sodium Azide Constituent: PBS |