Cat. No.: IBDA-431379
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Online InquiryTarget Information
| Target Name | TLR8 |
| Uniprot ID | Q9NR97 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide. |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Product Details
| Description | Rabbit monoclonal antibody to TLR8. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | WB: THP-1 treated with 12-O-Tetradecanoylphorbol-13-acetate (TPA) then with hIFN?, whole cell lysate IHC-P: Human spleen and B-cell lymphoma tissues. |
| Application | IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |