Cat. No.: IBDA-431375
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Online InquiryTarget Information
| Target Name | TLR8 |
| Uniprot ID | Q9NR97 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment corresponding to Human TLR8 aa 32-153. |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Product Details
| Description | Mouse monoclonal antibody to TLR8. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Affinity purified |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human TLR8 aa 32-153. |
| Positive Control | IHC-P: Human spleen and spleen carcinoma tissue. WB: pCMV6-ENTRY TLR8 cDNA transfected HEK-293T cell lysate. |
| Application | IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: PBS, 1% BSA, 50% Glycerol |
| Handling | Avoid freeze-thaw cycles. |