TLR9 Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	TLR9
Uniprot ID	Q9NR96
Cellular Localization	Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Immunogen	Recombinant fragment.
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Product Details

Description	Rabbit monoclonal antibody to TLR9 - BSA and Azide Free.
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment.
Positive Control	WB: Daudi, Raji and Ramos cell lysates. IHC-P: Human tonsil and breast carcinoma tissues.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.2 Constituent: PBS
Handling	Do not freeze.