TLR9 Monoclonal Antibody

Target Information

Target Name	TLR9
Uniprot ID	Q9NR96
Cellular Localization	Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Immunogen	Recombinant fragment within Human TLR9 (extracellular).
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Product Details

Description	FITC Mouse monoclonal antibody to TLR9.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG2a
Conjugation	FITC
Reactivity	Human
Immunogen	Recombinant fragment within Human TLR9 (extracellular).
Positive Control	RAW macrophages stimulated with IFN-gamma Flow Cyt (Intra): THP1 cells.
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	Preservative: 0.02% Sodium Azide Constituent: PBS, 1% BSA