Tofogliflozin (hydrate)

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Cat. No.: IBDI-434661

Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2. Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	SGLT \| Reactive Oxygen Species
Molecular Weight	404.45
Appearance	Solid
Synonyms	CSG-452 hydrate
SMILES	O[[email protected]@H]1[[email protected]@H](O)[[email protected]](O)[[email protected]@H](CO)O[[email protected]@]21OCC3=C2C=C(CC4=CC=C(CC)C=C4)C=C3.O
Purity	98.48%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.