Topoisomerase I inhibitor 5

Cat. No.: IBDI-435469

Topoisomerase I inhibitor 5 is an effective topoisomerase inhibitor with IC50 value of. Topoisomerase I inhibitor 5 can interfere with DNA and significantly inhibit the activity of Topoisomerase I. Topoisomerase I inhibitor 5 can arrest cell cycle at the G1 phase and induce MCF-7 cells apoptosis. Topoisomerase I inhibitor 5 has potency in reversing P-gp-mediated resistance to Adriamycin.

Product Details

Target	TopoisomeRase | DNA/RNA Synthesis | Apoptosis
Molecular Weight	372.46
SMILES	O=C(C1=CC=CC=C12)C3=CC=C(OCCN4C(C)CCCC4)C5=CC=NC2=C53

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.