Trabectedin-d3

Cat. No.: IBDI-432922

Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment.

Product Details

Target	Isotope-Labeled Compounds | Reactive Oxygen Species | Apoptosis
Molecular Weight	764.86
Appearance	Solid
Synonyms	Ecteinascidin 743-d3, ET-743-d3
SMILES	CC1=C(OCO2)C2=C([[email protected]](COC3=O)N4[[email protected]]([[email protected]@H]5SC[[email protected]]63C(C=C(OC([2H])([2H])[2H])C(O)=C7)=C7CCN6)([H])[[email protected]@H]8N(C)[[email protected]@H](CC9=CC(C)=C(OC)C(O)=C98)[[email protected]@H]4O)C5=C1OC(C)=O
Purity	99.08%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.