tri-GalNAc biotin

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Cat. No.: IBDI-435783

tri-GalNAc biotin is a small molecule lysosome targeting degrader. tri-GalNAc is a ligand of ASGPR (asialoglycoprotein receptor). tri-GalNAc biotin can facilitate the uptake of NeutrAvidin (NA) through ASGPR in liver cells. tri-GalNAc biotin delivers NeutrAvidin to lysosome for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC).

Size (Solid):

Product Details

Target	LYTACs
Molecular Weight	1916.19
Appearance	Solid
SMILES	O=C(CCNC(CCOCCOCCOCCNC(CCCC[[email protected]@H]1SC[[email protected]]([[email protected]]1([H])N2)([H])NC2=O)=O)=O)NC(COCCC(NCCCNC(CCCCO[[email protected]](O[[email protected]@H]3CO)[[email protected]@H]([[email protected]]([[email protected]]3O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[[email protected]](O[[email protected]@H]4CO)[[email protected]@H]([[email protected]]([[email protected]]4O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[[email protected]](O[[email protected]@H]5CO)[[email protected]@H]([[email protected]]([[email protected]]5O)O)NC(C)=O)=O)=O
Purity	99.40%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.