TRIF Monoclonal Antibody

Target Information

Target Name	TRIF
Immunogen	Recombinant fragment corresponding to Human TRIF aa 120-420.
Function	Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

Product Details

Description	Mouse monoclonal antibody to TRIF.
Host Species	Mouse
Clonality	Monoclonal
Purity	Affinity purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human, African green monkey
Immunogen	Recombinant fragment corresponding to Human TRIF aa 120-420.
Positive Control	WB: HEK-293T cell lysate transfected with pCMV6-ENTRY TRIF cDNA. HepG2, HeLa and COS-7 cell extracts.
Application	WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: PBS, 50% Glycerol, 1% BSA
Handling	Avoid freeze-thaw cycles.