TRIF Polyclonal Antibody

Target Information

Target Name	TRIF
Immunogen	Synthetic peptide within Mouse TRIF aa 100-200.
Function	Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

Product Details

Description	Rabbit polyclonal antibody to TRIF.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat
Immunogen	Synthetic peptide within Mouse TRIF aa 100-200.
Positive Control	WB: Mouse spleen, intestine and RAW 264.7 cell lysates. IHC-P: Mouse spleen tissue.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.02% Sodium Azide Constituent: PBS
Handling	Avoid freeze-thaw cycles.