TRIF (TICAM1) Monoclonal Antibody

Target Information

Target Name	TRIF (TICAM1)
Immunogen	Recombinant fragment.
Function	Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

Product Details

Description	Rabbit monoclonal antibody to TRIF.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment.
Positive Control	WB: Raji (human Burkitt's lymphoma b lymphocyte) whole cell lysate, Ramos (human burkitt's lymphoma b lymphocyte) whole cell lysate, HeLa (human cervix adenocarcinoma epithelial cell) whole cell lysate. IP: Raji (human Burkitt's lymphoma b lymphocyte).
Application	IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.