Trovafloxacin mesylate

Cat. No.: IBDI-435557

Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1.

Product Details

Target	Bacterial | TopoisomeRase | Antibiotic
Molecular Weight	512.46
Appearance	Solid
SMILES	O=C(C1=CN(C2=CC=C(F)C=C2F)C3=NC(N4C[[email protected]@]5([H])[[email protected]](N)[[email protected]@]5([H])C4)=C(F)C=C3C1=O)O.CS(=O)(O)=O
Purity	99.56%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.