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TTBK1-IN-2

Cat. No.: IBDI-433455

TTBK1-IN-2 (compound 29) is a potent Tau-Tubulin kinase (TTBK1) inhibitor with IC50s of 0.24 and 4.22 µM, respectively. TTBK1-IN-2 reveals good brain penetration in vivo and is able to reduce TDP-43 phosphorylation not only in cell cultures but also in the spinal cord of transgenic TDP-43 mice.

Size (Solid):

Product Details

Target Others
Molecular Weight 336.78
Appearance Solid
SMILES ClC1=CC=C(OC2=CC=C(C=C2)NC3=C4C(NC=C4)=NC=N3)C=C1
Purity 99.83%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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