Tunicamycin

Cat. No.: IBDI-430208

Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.Tunicamycin increases exosome release in cervical cancer cells.

Product Details

Target	Bacterial | Fungal | Influenza Virus | Antibiotic
Molecular Weight	844.94 (n=10)
Appearance	Solid
SMILES	O=C1NC(N([[email protected]]2[[email protected]](O)[[email protected]](O)[[email protected]@H](C(C[[email protected]@H]3[[email protected]](O)[[email protected]](O)[[email protected]@H](NC(/C=C/[(CH2) 8-11]C(C)C)=O)[[email protected]](O[[email protected]]4O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]4NC(C)=O)O3)O)O2)C=C1)=O
Structure Classification	Antibiotics
Purity	99.96%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.