TUS-007

Cat. No.: IBDI-435166

TUS-007 is a CANDDY molecular, modified from a proteasome inhibitor. However, TUS-007 hardly inhibits proteasome activity. TUS-007 is also an orally active and potent KRAS G12D/V degrader. TUS-007 can be applied in KRAS G12D/V chemical knockdown in cell-free. TUS-007 also exhibits tumor suppression.Note: CANDDY refers to Chemical knockdown with Affinity aNd Degradation DYnamics.

Product Details

Target	Ras
Molecular Weight	845.86
SMILES	O=C(C1=C(C=CC(Cl)=C1)Cl)NCC(N[[email protected]@H](CC(C)C)C(NCCCCCCC(N[[email protected]@H]([[email protected]](C)CC)C(NC2=CC=C3C(NC(CC4=CNC5=CC=CC=C45)=N3)=C2)=O)=O)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.