Type II topoisomerase inhibitor 1

Cat. No.: IBDI-433672

Type II topoisomerase inhibitor 1 is a potent and selective E. coli DNA gyrase inhibitor (IC50: 1.7 nM), and forms hydrogen bonds with Asp73 residue. Type II topoisomerase inhibitor 1 inhibits topoisomerase IV activity (IC50: 0.98 μM). Type II topoisomerase inhibitor 1 can be used in the research of antibacterial area.

Product Details

Target	DNA/RNA Synthesis | TopoisomeRase | Bacterial
Molecular Weight	337.33
SMILES	CNC1=CC=CC2=C1NC(C(C(NC3=CC=C(C=C3)C(O)=O)=O)=C2)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.