UK-101

Cat. No.: IBDI-434914

UK-101 is a potent and selective immunoproteasome β1i (LMP2) inhibitor with an IC50 value of 104 nM, displays 144- and 10-fold selectivity over β1c (IC50=15 μM) and β5 subunit (IC50=1 μM), respectivey. UK-101 induces cell apoptosis and can be used for the study of prostate cancer.

Product Details

Target	Proteasome | Apoptosis
Molecular Weight	484.74
SMILES	O=C([[email protected]]1(CO1)CO[Si](C)(C)C(C)(C)C)[[email protected]](CC(C)C)NC([[email protected]](C)NC(CCCCCC)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.