Cat. No.: IBDA-432182
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Online InquiryTarget Information
| Target Name | uPA Receptor/U-PAR |
| Uniprot ID | Q03405 |
| Cellular Localization | Secreted and Cell membrane. |
| Immunogen | Recombinant fragment. |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
Product Details
| Description | Rabbit monoclonal antibody to uPA Receptor/U-PAR. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Recombinant fragment. |
| Positive Control | WB: Untreated bEnd.3 whole cell lysate. RAW264.7 whole cell lysate, Mouse lung, kidney and spleen tissue lysate. IHC-P: Mouse kidney and spleen tissue. Mouse head and neck squamous cell carcinoma. IP: bEnd.3 whole cell lysate. |
| Application | IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 40% Glycerol, 59% PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |