Cat. No.: IBDA-432184
Size:
Online InquiryTarget Information
| Target Name | uPA Receptor/U-PAR |
| Uniprot ID | Q03405 |
| Cellular Localization | Secreted and Cell membrane. |
| Immunogen | Recombinant fragment. |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
Product Details
| Description | Rabbit monoclonal antibody to uPA Receptor/U-PAR. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment. |
| Positive Control | ICC/IF: U937 cells treated with 200 nM TPA for 72 hours. Flow Cyt: U937 cells treated with 200 nM TPA for 72 hours. IP: U937 treated with 200 nM TPA for 72 hours whole cell lysate. |
| Application | Flo, ICC/IF, IP |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |