Ursodeoxycholic acid-2,2,4,4-d4

Cat. No.: IBDI-432247

Ursodeoxycholic acid-2,2,4,4-d4 is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection.

Product Details

Target	Isotope-Labeled Compounds
Molecular Weight	396.60
SMILES	C[[email protected]@]12[[email protected]]([[email protected]]3([[email protected]@]([[email protected]]4(C)[[email protected]](C[[email protected]@H]3O)(C([[email protected]](O)C(C4)([2H])[2H])([2H])[2H])[H])(CC1)[H])[H])(CC[[email protected]@]2([[email protected]@H](CCC(O)=O)C)[H])[H]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.