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Uzansertib phosphate

Cat. No.: IBDI-435628

Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines.

Size (Solid):

Product Details

Target Pim
Molecular Weight 611.51
Appearance Solid
Synonyms INCB053914 phosphate
SMILES O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[[email protected]]4O)=C3N5C[[email protected]@H](N)[[email protected]](O)[[email protected]@H](C)C5.OP(O)(O)=O
Purity 99.39%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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