Valproic acid-d15

Cat. No.: IBDI-431651

Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

Product Details

Target	HDAC | Autophagy | Mitophagy | HIV | Notch | Endogenous Metabolite
Molecular Weight	159.30
Appearance	Liquid
Synonyms	VPA-d15, 2-Propylpentanoic Acid-d15
SMILES	[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C(C(O)=O)([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
Purity	≥99.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Pure form: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.