Verucopeptin

Cat. No.: IBDI-438434

Verucopeptin is a potent?HIF-1 (IC50=0.22 μM) inhibitor and decreases the expression of HIF-1 target genes and HIF-1α protein levels. Verucopeptin strongly inhibits v-ATPase activity?by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Verucopeptin exhibits antitumor activity against multidrug resistance (MDR)?cancers and can be used for cancer research.

Product Details

Target	HIF/HIF Prolyl-Hydroxylase | Proton Pump | Endogenous Metabolite
Molecular Weight	896.08
Appearance	Solid
Sequence Shortening	L-{Aaa}-G-{Sar}-G-{Sar} Lactone:(Leu1-Sar6)
Purity	98.42%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -80°C/2 years; -20°C/1 year *In solvent : -80°C, 6 months; -20°C, 1 month
Handling	Sealed storage, away from moisture
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.