Vorinostat-d5

Cat. No.: IBDI-436549

Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification.

Product Details

Target	HDAC | Autophagy | Mitophagy | Filovirus | Apoptosis | HPV
Molecular Weight	269.35
Appearance	Solid
Synonyms	SAHA-d5, Suberoylanilide hydroxamic acid-d5
SMILES	O=C(NO)CCCCCCC(NC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
Purity	≥99.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.