XST-14

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Cat. No.: IBDI-436820

XST-14 is a potent, competitive and highly selective ULK1 inhibitor with an IC50 of 26.6 nM. XST-14 induces autophagy inhibition by reducing the phosphorylation of the ULK1 downstream substrate. XST-14 induces apoptosis in hepatocellular carcinoma (HCC) cells and has antitumor effects.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	ULK \| p38 MAPK \| TGF-β Receptor \| Anaplastic lymphoma kinase (ALK) \| CaMK \| Apoptosis
Molecular Weight	291.34
Appearance	Solid
SMILES	O=C(OC)C1=CC2=C(OC(C)C)C=C(OC(C)C)C=C2N1
Purity	99.69%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.