(Z)-Guggulsterone

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Cat. No.: IBDI-430974

(Z)-Guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis. (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Apoptosis \| VEGFR \| Akt \| Angiotensin-converting Enzyme (ACE) \| SARS-CoV \| FXR \|
Molecular Weight	312.45
Appearance	Solid
SMILES	C[[email protected]@]1(/C2=C/C)[[email protected]](CC2=O)([H])[[email protected]@]3([H])[[email protected]]([[email protected]@]4(C(CC3)=CC(CC4)=O)C)([H])CC1.[Z]
Structure Classification	Steroids
Purity	99.30%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.