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ZXH-4-130 TFA

Cat. No.: IBDI-434935

ZXH-4-130 TFA is a highly potent and selective degrader of CRBN. ZXH-4-130 is a CRBN-VHL compound (hetero-PROTAC). ZXH-4-130 TFA induces ~80% CRBN degradation at 10 nM in MM1.S cells.

Size (Solid):

Product Details

Target PROTACs
Molecular Weight 985.08
Appearance Solid
SMILES O=C([[email protected]]1N(C([[email protected]@H](NC(CCCCCCCCCCOC2=CC=CC(C(N3C(CC4)C(NC4=O)=O)=O)=C2C3=O)=O)C(C)(C)C)=O)C[[email protected]](O)C1)NCC5=CC=C(C6=C(C)N=CS6)C=C5.OC(C(F)(F)F)=O
Purity 99.53%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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