Unlock Insights into IBD Research | Specialized Experimental Model Solutions

At Ace Therapeutics, we offer well-established DSS-induced acute and chronic colitis models, designed to support preclinical IBD research and drug development.

Why Choose Our DSS-Induced Colitis Models?

• Clinically Relevant: Mimics key aspects of human ulcerative colitis, including mucosal barrier disruption, colon shortening, and inflammatory cell infiltration.
• Mimics key aspects of human ulcerative colitis, including mucosal barrier disruption, colon shortening, and inflammatory cell infiltration.
• Customizable Across Species: Available in mice, rats, rabbits, canines, and non-human primates, tailored to your specific research needs.

Comprehensive Readouts and Testing Capabilities

We provide a full spectrum of downstream testing services to maximize the value of your study:

• In-Life Assessments: Body weight, Disease Activity Index (DAI), colon length/weight ratio
• Histopathology: H&E staining, crypt damage scoring, inflammatory cell infiltration
• Molecular & Immunological Analysis: Cytokine profiling, gene/protein expression, immune cell phenotyping
• Microbiome Evaluation: Gut microbial composition and functional analysis
• Advanced Imaging: Endoscopy, CT, MRI, PET/CT to visualize colitis severity and disease progression

Partner with Ace Therapeutics

With our reproducible and validated DSS-induced colitis models, we help researchers accelerate discovery, de-risk development pipelines, and generate data with translational relevance to human IBD. Whether your goal is to evaluate drug efficacy, explore mechanisms of action, or identify predictive biomarkers, our team is ready to support your research from study design to comprehensive analysis.

With our reproducible and validated DSS-induced colitis models, we help researchers accelerate discovery, de-risk development pipelines, and generate data with translational relevance to human IBD. Whether your goal is to evaluate drug efficacy, explore mechanisms of action, or identify predictive biomarkers, our team is ready to support your research from study design to comprehensive analysis.

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