Unlock The One-stop Anti-CD40-induced Colitis Model Standardized Protocol

Looking to accelerate your IBD drug discovery? Download our protocol of Anti-CD40-induced colitis in Rag2-/- mice mice—a robust, reproducible, and rapid model to study innate immune responses in IBD. This comprehensive guide covers everything from induction steps to histopathology, flow cytometry, and gene expression profiling. It's an essential resource for researchers aiming to explore IL-23/IL-22 signaling, gut-resident macrophages, and ILC3 activity in colitis.

Why does this protocol enhance your research productivity?

Streamlined, Ready-to-Use Workflow

Skip the trial-and-error. This protocol provides a fully optimized and step-by-step guide for inducing anti-CD40-mediated colitis in Rag2-/- mice, saving valuable time in study setup and execution.

Multiparametric Data from a Single Model

The protocol integrates histopathology, cytokine analysis, gene expression profiling, and flow cytometry, allowing you to generate comprehensive datasets from the same experiment, maximizing output per animal.

Ideal for Target Validation

By focusing on IL-23/IL-22 pathways and innate immune cell function, this model is highly relevant for validating novel IBD therapeutic targets in early discovery stages.

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