Customized Biospecimen Collection and Analysis
Preclinical Hematology R&D Solutions
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Customized Biospecimen Collection and Analysis

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At Ace Therapeutics, we specialize in providing customized biospecimen collection and analysis services tailored to the unique demands of preclinical hematologic disease research. Our services are designed to generate high-quality, well-annotated biospecimens that enable in-depth molecular, cellular, and biochemical analyses in a wide array of preclinical models. With a focus on reliability, scalability, and scientific precision, our biospecimen services support biomarker identification, mechanism-of-action studies, and therapeutic validation.

Why Biospecimen Customization Matters in Hematology

Blood diseases exhibit complex pathophysiology influenced by genetic, molecular, and environmental factors. Standardized biospecimen protocols often fail to capture disease-specific nuances. Ace Therapeutics addresses this gap through

  • Targeted sample types including peripheral blood, bone marrow, plasma, serum, and spleen tissues.
  • Longitudinal collection in disease models to track temporal biomarker changes.
  • Stability-optimized handling preserving sample integrity for downstream applications.

Comprehensive Biospecimen Collection Capabilities

We support diverse sample types and collection strategies to accommodate various stages of preclinical hematology studies.

Sample Types Details
Peripheral Blood Serial collection for hematological and immunophenotyping studies
Bone Marrow Aspiration or isolation from femur/tibia for progenitor and stem cell analysis
Plasma and Serum Separated using validated centrifugation protocols for proteomic and metabolomic assays
Spleen Tissue Dissected for immunological or gene expression profiling
Longitudinal Sampling Enables temporal biomarker analysis in progressive or therapeutic study designs

We ensure metadata-rich biobanking with full traceability, including animal identifiers, treatment regimens, timepoints, and environmental parameters.

Multiparametric Analysis Services

We offer integrated downstream analysis optimized for hematologic biospecimens, ensuring maximum data extraction and translational value.

Hematological profiling

  • White blood cell differentials
  • Platelet and red blood cell counts

Biochemical assays

  • Cytokine and chemokine quantification
  • Iron metabolism parameters

Molecular assays

  • Gene expression analysis
  • Protein analysis
  • DNA mutation and methylation analysis

Our extraction protocols are optimized for hematologic samples, ensuring high-quality RNA, DNA, and protein even from small-volume or challenging specimens.

Integrated Biobanking and Sample Logistics

We manage biospecimen handling with meticulous attention to detail to maintain sample integrity throughout the study lifecycle.

  • Temperature-controlled storage and shipping
  • Barcoding and digital tracking for sample traceability
  • Standardized metadata capture (e.g., collection date, experimental group, animal ID)
  • Optional long-term storage for retrospective studies

All collection and processing steps are coordinated to support reproducibility and downstream analysis compatibility.

Applications of Our Services

Application Area How Our Biospecimens Support It
Biomarker Discovery Longitudinal sample collection for tracking changes over time
Therapeutic Mechanism Studies Isolation of specific immune or progenitor cell populations for pathway analysis
Pharmacodynamics Evaluation Correlation of biomolecular changes with drug exposure
Molecular Diagnostics Development High-integrity DNA/RNA for assay development
Translational Research Bridging in vivo models to human disease mechanisms through multi-omics approaches

Contact us today to discuss how our customized biospecimen collection and analysis services can align with your project goals.

Frequently Asked Questions (FAQs)

What types of animal models do you support for biospecimen collection?

We support a wide variety of hematologic disease models, including murine models of leukemia, anemia, lymphoma, and bone marrow failure syndromes. Custom model integration is also available.

Can you accommodate serial blood collections in longitudinal studies?

Yes, we provide serial peripheral blood collection to support time-course analyses, ideal for biomarker tracking or therapeutic monitoring.

What types of analyses can you perform on collected biospecimens?

We offer hematologic, biochemical, molecular, and proteomic analyses, including custom assay integration upon request.

How do you ensure sample integrity during processing and storage?

We use validated protocols for collection and storage, along with barcode-based sample tracking and environment-controlled biobanking facilities.

Can biospecimens be stored for future use or re-analysis?

Yes, long-term storage is available, with full traceability and metadata for each sample to enable retrospective studies.

HOW WE WORK

Make Order

Make Order

Experimental Scheme

Experimental Scheme

Implementation

Implementation

Conclusion

Conclusion