Ace Therapeutics stands at the forefront of preclinical contract research organizations, specializing in providing comprehensive services for obesity research. We are dedicated to advancing the development of effective anti-obesity therapies by offering high-quality, insightful preclinical solutions. Our core service, Real-Time Feeding Behavior Analysis, provides a critical tool for gaining a comprehensive understanding of obesity-related mechanisms and evaluating the efficacy of potential drug candidates.
Traditional methods of assessing food intake often fall short in capturing the full complexity of an animal's feeding behavior. Simply measuring total daily food consumption provides limited information about the intricate patterns of eating that are crucial for understanding the underlying mechanisms of obesity and the impact of potential treatments. Real-time monitoring offers significant advantages by providing a dynamic and detailed view of an animal's interaction with food. This allows for the precise capture of:
This level of detail provides valuable insights into appetite regulation and metabolic balance in preclinical models. Furthermore, it contributes to a better understanding of the complex motivations and compulsions that can drive overeating in obese models.
Fig.1. AI development for detecting the opening and closing mouth movements of mice. (Kitaoka, Y., et al. 2023)
Ace Therapeutics offers comprehensive real-time feeding behavior analysis services, meticulously designed to provide our clients with a detailed and multifaceted dataset on feeding behavior. We monitor key parameters including:
We utilize advanced technology and automated feeding systems equipped with sensitive sensors to ensure precise measurements. Our experienced team designs and executes customized studies tailored to your specific research needs and various animal models, including diet-induced obesity (DIO) and genetic models.
Multi-sensor arrays record feeding events 24/7, minimizing human intervention and reducing observational bias.
Machine learning models classify distinct feeding phases (e.g., exploratory nibbling vs. sustained consumption) and identify anomalies linked to pharmacological or genetic interventions.
Synchronize feeding data with physiological metrics such as energy expenditure, locomotor activity, and glucose homeostasis for holistic metabolic profiling.
Partner with Ace Therapeutics to gain deeper, more insightful data from your preclinical obesity research. Our real-time feeding behavior analysis services provide the critical information you need to accelerate the development of innovative anti-obesity therapies.
Parameter | Description | Relevance to Obesity Research |
Meal Frequency | Number of eating episodes per unit of time | Indicates changes in appetite and satiety signals. |
Average Meal Size | Average amount of food consumed per eating episode | Reflects the impact of treatments on satiety. |
Eating Rate | Speed at which food is consumed | May indicate changes in motivation to eat or physiological responses. |
Total Food Intake | Total amount of food consumed over a specific period | Provides an overall measure of energy intake. |
Inter-Meal Interval | Time elapsed between meals | Reflects satiety duration and frequency of hunger cues. |
Duration of Eating Episodes | Length of each individual eating event | Can indicate changes in satiety or palatability. |
Water Intake | Total amount of water consumed | Important for overall health assessment. |
Food Selection (if offered) | Preference for different dietary components | Reveals changes in dietary preferences. |
Eating Patterns | Detailed analysis of how food is consumed (e.g., nibbling) | Provides insights into behavioral aspects of feeding. Useful for identifying specific behaviors like binge eating. |
Real-time feeding behavior analysis is a versatile tool with broad applications in preclinical obesity research, including:
This approach is particularly valuable in the context of multi-target and combination therapies, allowing for a comprehensive understanding of their combined effects on feeding behavior.
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