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Myh7-R403Q

Cat. No: CDM0109

Nomenclature: C57BL/6J-Myh7^{em1Cin (R403Q)}

Strain State: Embryo cryopreservation

Gene Summary
Human Ortholog	MYH7
MGI ID	2155600
Gene ID	4625
Target Name	Myh7
Synonyms	B-MHC, MyHC-, Myhcb, MyHC-I, Myhc-b, betaMH, beta-MH, betaMHC, beta-MHC, myHC-beta, myHC-slow, MYH-beta/slow

Model Description
Description	These mice carry a dominant-negative pathogenic variant in β-myosin (MYH7)—a well-characterized mutation that augments myocardial contractility and reliably induces hypertrophic cardiomyopathy (HCM).
Disease Connection	Myocardial Hypertrophy, Heart Failure
Phenotype(s)	6360218

! For research use only. Not intended for any clinical use.