Patch Clamp Platform for Cardiovascular Diseases
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As a sophisticated electrophysiological method, patch clamp technique employs microelectrodes to control cellular voltage or current, allowing precise recording of ion channel activity. Ace Therapeutics' dedicated platform applies this technique to cardiovascular ion channel research and drug screening, providing unique insights into channel function and drug interactions.
Principle of Patch Clamp Technique
Widely utilized in cardiovascular disease research, patch clamp technique allows diverse applications that significantly enhance our understanding of cardiovascular diseases and drive the development of targeted therapies.
- Ion Channel Function Studies
Investigating abnormalities in sodium, potassium, calcium, and other ion channels to uncover the mechanisms underlying cardiac arrhythmias.
- Cell Signaling Research
Exploring the regulation of ion channels by signaling molecules such as G proteins and cAMP.
- Gene Mutation and Disease Research
Analyzing the impact of gene mutations on ion channel function and studying how these mutations lead to electrophysiological abnormalities in cardiomyocytes.
- Functional Studies of Ion Channels in Cardiovascular Diseases
Our advanced patch clamp technique platform allows us to directly measure the current of individual ion channels, offering unparalleled insights into their roles within the cardiovascular system.
- Analyzing Ion Channel Abnormalities in Arrhythmias
Our platform specializes in investigating arrhythmia-related ion channel abnormalities, including long QT syndrome caused by sodium channel mutations and atrial fibrillation linked to potassium channel dysfunction.
- Cardiovascular Drug Screening and Development
Our patch clamp technique platform enables the assessment of drug effects on ion channels, supporting the screening and optimization of cardiovascular drugs, including antiarrhythmics and antihypertensives.
- Cardiomyocyte Electrophysiological Characterization
We utilize the patch clamp technique to study the electrophysiological properties of cardiomyocytes, such as action potentials and excitation-contraction coupling.
At Ace Therapeutics, through our advanced patch clamp technique platform, we contribute to research by providing high quality research solutions to researchers in the field of cardiovascular disease. If you are interested in our services, please do not hesitate to contact us.
! All of our services and products are intended for preclinical research use only and cannot be intended for any clinical use.
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