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Recombinant Human SOD2/Mn-SOD Protein (His Tag, Human Cells)
| Target Information | |
|---|---|
| Target Name | SOD2/Mn-SOD |
| Synonyms | Superoxide Dismutase [Mn] Mitochondrial; SOD2 |
| UniProt ID | P22934 |
| Accession | P04179 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Human |
| Tag | C-6His |
| Molar Mass | 23.2 kDa |
| Sequence | Ser 27-Asn 756 |
| Background |
|---|
| Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide; a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer; while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites. |
| Properties | |
|---|---|
| Purity | >97% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH8.0. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
| Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.