12-HETE

Product Details
Formula	C20H32O3
Molecular Weight	320.47
Appearance	Liquid
Purity	≥95.0%
Smiles String	CCCCC/C=C\CC(O)/C=C/C=C\C/C=C\CCCC(O)=O

Storage & Handling
Shipping	Room temperature.
Storage	Solution, -20 °C, 2 years

12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway.12-HETE has both anti-thrombotic and pro-thrombotic effects. 12-HETE is a neuromodulator.

! For research use only. Not intended for any clinical use.