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Abcb4-KO

Cat. No: CDM0108

Nomenclature: C57BL/6J-Abcb4^em1

Strain State: Embryo cryopreservation

Gene Summary
Human Ortholog	ABCB4
MGI ID	97569
Gene ID	5244
Target Name	Abcb4
Synonyms	Mdr2, Pgy2, Pgy-2, mdr-2

Model Description
Description	These Abcb4-KO mice lack both the gene and its protein product, exhibiting hepatomegaly, elevated liver-injury biomarkers, and increased total bilirubin.
Disease Connection	Progressive Familial Intrahepatic Cholestasis Type 3 (PFIC3)
Phenotype(s)	6492679

! For research use only. Not intended for any clinical use.