AV123

Product Details
Formula	C11H14N4O2
Molecular Weight	234.25
Smiles String	O=[N+](C1=CC=C2C(NC(NCCCC)=N2)=C1)[O-]

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor (IC50=12.12 µM). AV123 blocks the TNF-α-induced necroptotic (EC50=1.7 μM) but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases.

! For research use only. Not intended for any clinical use.