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AZ3976

Cat. No: CDIA-1810

CAS. No.: 1418747-15-5

Size: 50 mg

Price: Inquiry

Product Details
Formula	C15H19N5O3
Molecular Weight	317.34
Smiles String	O=C1N=C(NC2CN(C2)C(OC(C)(C)C)=O)NC3=NC=CC=C13

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Description

AZ3976 is a potent plasminogen activator inhibitor type 1 (PAI-1) inhibitor with an IC50 value of 26 μM in an enzymatic chromogenic assay. AZ3976 is active with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 does not bind to active PAI-1 but bound reversibly to latent PAI-1. AZ3976 inhibits PAI-1 by enhancing the latency transition of active PAI-1. AZ3976 displays profibrinolytic activities in a human plasma clot lysis assay.

! For research use only. Not intended for any clinical use.