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BQ-123

Cat. No: CDIA-0275

CAS. No.: 136553-81-6

Size: 1 mg

Price: Inquiry

Product Details
Formula	C31H42N6O7
Molecular Weight	610.70
Appearance	Solid
Purity	99.44%
Smiles String	O=C(N[[email protected]](C(N(CCC1)[[email protected]]1([H])C2=O)=O)([H])CC(O)=O)[[email protected]](NC([[email protected]@H](NC([[email protected]](N2)C(C)C)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.

! For research use only. Not intended for any clinical use.