Products

Online Inquiry

* First Name

* Last Name

Phone

* Business Email

Company/Institution

Job Title

* Services or Products of Interest

When do you expect your project to start?

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

CCG258208 hydrochloride

Cat. No: CDIA-0384

Synonyms: GRK2-IN-1 hydrochloride

Size: 1 mg

Price: Inquiry

Product Details
Formula	C24H26ClFN4O4
Molecular Weight	488.94
Appearance	Solid
Purity	98.76%
Smiles String	FC1=C(C(NCC2=NNC=C2)=O)C=C([[email protected]]3[[email protected]](COC4=CC=C(OCO5)C5=C4)CNCC3)C=C1.[H]Cl

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM) while maintaining 230-fold selectivity over GRK5 (IC50=7.09 μM) and more than 2500-fold selectivity over GRK1 (IC50=87.3 μM), PKA, and ROCK1. CCG258208 hydrochloride can be used in heart failure research.

! For research use only. Not intended for any clinical use.